Synthesis, Characterization and Biological Approach of N’-(3-(Hydroxy Imino) Butan-2-ylidene)-2-Oxo-2H-Chromene-3-Carbohydrazide Complexes

Coumarin family considered an essential heterocyclic compounds which belong to benzopyrones family that contains of phenyl ring fused with a pyrone ring. Coumarin classified into six groups count on chemical structure of compounds and these group are simple (coumarins, bi coumarins, phenyl coumarins, pyrano coumarins, furano coumarins and dihydrofurano coumarins)Coumarin mainly existed in plant kingdom such as (leaves, roots, stems and fruits). Besides, they found in different oils as ‘’lavender oil, cinnamon bark, oil and cassia oil’’.

Moreover, coumarin derivatives have changed uses such as ‘’optical brightening agents, laser dyes, cosmetic industry agrochemical industries and food additives’’. Furthermore, Coumarin derivatives have important biological activity as antibacterial, antifungal, anti-oxidant, anti-allergic, antiinflammatory, anti-thrombotic, hepatoprotective, anti-viral, anticarcinogenic activities. So, this study involved the biological estimation of N’-(3-(hydroxyimino) butan-2-ylidene)-2-oxo-2Hchromene- 3-carbohydrazide (H2L) and its metal complexes.