Showing posts with label analytical chemistry journal. Show all posts
Showing posts with label analytical chemistry journal. Show all posts

Monday, 20 March 2017

A Study of the Effect of Pyrites and Rhizobium Inoculation on Chlorophyll and Sugar Content in Black Gram under Sodicity Stress Condition


Calcareous soils have resulted in precipitation of CaCO3 from water of some rivers which contain high amount of CaH(CO3)2. The tropical aridity creates reaction resulting in accumulation of salts. Most of the waterof uplands is lost due to runoff and transpiration reducing effective leaching. Precipitation of calcium increases sodium concentration which is further augmented by high RSC of the available water resources. Salinity is the major yield reducing factor in legume cultivation as legumes are salt sensitive crop, especially in the seedling stages where they are most susceptible to damage due to water stress and ion-imbalance.

Black Gram

In saline soils, many environmental factors such as soil pH, water deficiency and nutrient deficiency are reported in Ref.that the seedling stage suffers most damage due to ion-imbalance and thus, other physiological processes are negatively affected during the growth of theplant especially photosynthesis. Ref.reported that during long term exposure to salinity, plants experience premature senescence of adult leaves and root nodules which reduce the net photosynthetic area available to support continued growth of the plant. Thus, bio-synthesis of sugar and nitrogen fixation are negatively affected.

Wednesday, 16 November 2016

Role of Schiff Base in Drug Discovery Research



Compounds having imine or azomethine (–C=N–) functional group are known as Schiff bases. They were first reported in 1864 by German Chemist, Hugo Schiff and hence they are named so. For the synthesis of Schiffbase, a number of methods have been described in literature. These are now synthesized by a simple one pot condensation of an various amines/hydrazides with carbonyl compounds, water is eliminated during condensation process.Schiff bases are synthesis from simple reaction between acetone and primary amine. Water is byproduct in this reaction.Other name for Schiff bases are imine or azomethine.

Drug Discovery Research

Schiff bases form an backbone for large number of organic compounds and have a enormous applications in many fields. Structurally these arenitrogen derivatives of carbonyl compounds in which the (C=O) group has beenreplaced by an (C=N) group. Schiff bases have also received a great attention because of their potential biological activities such as antiinflammatory, analgesic, antimicrobial, anticancer, antioxidant and so forth.

Saturday, 3 September 2016

Electrochemical Biosensors; A Promising Tool in Pharmaceutical Analysis

In analytical chemistry, the main challenges are concerned with rapid and simultaneous detection of compounds occurred in clinical, environmental and food samples. Due to this reason biosensors are called as promising tools which can be used for detecting many chemical and biological parameters. It consists of a bio component used in the molecular recognition and a transducer, electronic signal processor. The main principle of biochemical sensors is the specific molecular recognition of the analyte which can be performed by the use of enzymes, antibodies, nucleic acids, germs, cells and tissues. In this reaction, some physiochemical changes may takes place between the bio component and the analyte, which is converted into electrical signal with the transducer. 

Pharmaceutical Analysis

Researchers have studied that these biosensors are divided into three types such as amperometric and potentiometric, conductive. In electrochemical biosensor the transducer act as an electrode and the transduction is mostly realized by means of amperometry or potentiometry. According to scientific significance the two primary classes of electrochemical biosensors are the chemical and DNA biosensors.