Relation Between Red Cell Distribution Width and Serum Lipoprotein(a) in Healthy Adult Men

Coronary Artery Disease (CAD), cancer, stroke, pulmonary diseases, obesity, and other pathologies related metabolic syndrome are the leading causes of mortality and morbidity in the modern world. Some biologic markers are associated withincreased risk for these diseases. Insulin resistance, dyslipidemia, increased activation of the coagulation cascade, elevations in cell adhesion molecules and in molecules associated with inflammation play important role in pathogenesis of these diseases. High blood levels of Lipoprotein (a) [Lp(a)] has been identified as a risk factor for cerebrovascular disease (CVD), atherosclerosis, thrombosis, and stroke.

Red cell distribution width (RDW) is a measure of the variability in size of circulating erythrocytes. An increased RDW can result from conditions that modify the shape of red bloodcells due to the premature release of immature cells into the bloodstream. Recently, it has showed that RDW may be used as a marker for some diseases.