Metabolic syndrome (MetS) is a cluster of cardiovascular
(CV) risk factors, including central obesity, glucose homeostasis, insulin
resistance, hypertension and atherogenic dyslipidemia, appears to have anincreased prevalence worldwide. Recent clinical and observation trials have
shown that the patients with MetS exhibit near 2-fold increased risk of CV
disease and events, asymptomatic atherosclerosis, all cause and CV death rate.
There are evidence regarding the pivotal role of vitamin
D in pathogenesis of CV disease, diabetes mellitus, obesity, and MetS. Thereliable indicator of body vitamin D status is serum concentration of25-hydroxyvitamin D [25(OH)D3]. Low serum 25(OH)D3 levels have been directly
linked to MetS, whereas the overall risk of MetS in general population was not
probably associated with 25(OH)D3 concentration.
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